{"id":1013,"date":"2021-06-10T10:20:39","date_gmt":"2021-06-10T03:20:39","guid":{"rendered":"https:\/\/iptc.vn\/sip\/?p=1013"},"modified":"2021-06-11T10:02:30","modified_gmt":"2021-06-11T03:02:30","slug":"tra-giai-lo-au-assamica-ms-016","status":"publish","type":"post","link":"https:\/\/iptc.vn\/sip\/tra-giai-lo-au-assamica-ms-016\/","title":{"rendered":"Tr\u00e0 gi\u1ea3i lo \u00e2u Assamica (MS: 016)"},"content":{"rendered":"

\"\"<\/p>\n

 <\/p>\n

T\u00caN T\u00c1C GI\u1ea2\/ NH\u00d3M T\u00c1C GI\u1ea2<\/strong><\/p>\n

Nguy\u1ec5n Long Ho\u00e0ng, Ph\u1ea1m Thanh Th\u1ea3o Nguy\u00ean, Nguy\u1ec5n Ho\u00e0ng Phong, L\u00e2m Hi\u1ec1n X\u01b0\u01a1ng, Tr\u1ea7n T\u01b0\u1eddng Vy\u00a0–\u00a0Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc B\u00e1ch Khoa \u0110HQG-HCM<\/p>\n

V\u00f5 Vi\u1ebft Ti\u1ebfn –\u00a0Tr\u01b0\u1eddng \u0110\u1ea1i h\u1ecdc T\u00f4n \u0110\u1ee9c Th\u1eafng TP HCM<\/p><\/blockquote>\n

 <\/p>\n

V\u1ea4N \u0110\u1ec0 C\u1ea6N GI\u1ea2I QUY\u1ebeT<\/strong><\/p>\n

\u00a0<\/em>M\u1ea5t ng\u1ee7 v\u00e0 Stress hi\u1ec7n \u0111ang tr\u1edf th\u00e0nh m\u1ed9t v\u1ea5n \u0111\u1ec1 nh\u1ee9c nh\u1ed1i m\u00e0 h\u1eadu qu\u1ea3 th\u1ea3m kh\u1ed1c c\u1ee7a n\u00f3 ng\u00e0y c\u00e0ng xu\u1ea5t hi\u1ec7n d\u00e0y \u0111\u1eb7c tr\u00ean c\u00e1c m\u1eb7t b\u00e1o. Nghi\u00ean c\u1ee9u v\u1ec1 t\u00e2m l\u00fd c\u1ee7a t\u1ed5 ch\u1ee9c \u201cGlobal Relaxation\u201d ch\u1ec9 ra r\u1eb1ng r\u1eb1ng h\u01a1n 51% ng\u01b0\u1eddi d\u00e2n tr\u00ean th\u1ebf gi\u1edbi ng\u1ee7 \u00edt h\u01a1n h\u1ecd c\u1ea7n (hay n\u00f3i kh\u00e1c \u0111i l\u00e0 thi\u1ebfu ng\u1ee7); trung b\u00ecnh m\u1ed9t ng\u01b0\u1eddi lao \u0111\u1ed9ng d\u00e0nh t\u1edbi 7 ng\u00e0y m\u1ed9t n\u0103m ch\u1ec9 \u0111\u1ec3 b\u01b0\u1edbc v\u00e0o gi\u1ea5c ng\u1ee7 (kh\u00f3 ng\u1ee7); 80% ng\u01b0\u1eddi d\u00e2n tr\u00ean th\u1ebf gi\u1edbi d\u00f9ng 2 ng\u00e0y cu\u1ed1i tu\u1ea7n \u0111\u1ec3 ng\u1ee7 b\u00f9 cho 5 ng\u00e0y l\u00e0m vi\u1ec7c [1]. T\u1eeb c\u00e1c s\u1ed1 li\u1ec7u tr\u00ean c\u00f3 th\u1ec3 d\u1ec5 d\u00e0ng th\u1ea5y r\u1eb1ng, \u201cgi\u1ea5c ng\u1ee7 t\u1ef1 nhi\u00ean\u201d c\u1ee7a m\u1ed7i ng\u01b0\u1eddi trong ch\u00fang ta \u0111ang b\u1ecb \u0111e d\u1ecda nghi\u00eam tr\u1ecdng.<\/p>\n

\"\"<\/p>\n

H\u00ecnh 1. <\/strong>Hi\u1ec7n tr\u1ea1ng v\u1ec1 gi\u1ea5c ng\u1ee7 c\u1ee7a c\u00e1c qu\u1ed1c gia tr\u00ean th\u1ebf gi\u1edbi.<\/p>\n

Theo th\u1ed1ng k\u00ea c\u1ee7a B\u1ed9 Y t\u1ebf n\u0103m 2020<\/strong>, c\u1ea3 n\u01b0\u1edbc c\u00f3 \u0111\u1ebfn 15%<\/strong> d\u00e2n s\u1ed1 c\u00f3 c\u00e1c v\u1ea5n \u0111\u1ec1 v\u1ec1 s\u1ee9c kh\u1ecfe t\u00e2m th\u1ea7n, \u0111\u1eb7c bi\u1ec7t l\u00e0 c\u00e1c r\u1ed1i lo\u1ea1n lo \u00e2u, tr\u1ea7m c\u1ea3m, g\u00e2y \u1ea3nh h\u01b0\u1edfng t\u1edbi s\u1ee9c kh\u1ecfe c\u0169ng nh\u01b0 ch\u1ea5t l\u01b0\u1ee3ng cu\u1ed9c s\u1ed1ng.<\/p>\n

\u0110\u00e1ng b\u00e1o \u0111\u1ed9ng khi s\u1ed1 ng\u01b0\u1eddi b\u1ecb stress ng\u00e0y c\u00e0ng c\u00f3 chi\u1ec1u h\u01b0\u1edbng gia t\u0103ng v\u00e0 ph\u1ea7n l\u1edbn trong \u0111\u1ed9 tu\u1ed5i lao \u0111\u1ed9ng. Trong 10 b\u1ec7nh t\u00e2m th\u1ea7n th\u01b0\u1eddng g\u1eb7p nh\u01b0 tr\u1ea7m c\u1ea3m, \u0111\u1ed9ng kinh, r\u1ed1i lo\u1ea1n lo \u00e2u, stress, t\u00e2m th\u1ea7n ph\u00e2n li\u1ec7t…, b\u1ec7nh nh\u00e2n d\u01b0\u1edbi 30 tu\u1ed5i<\/strong> chi\u1ebfm t\u1edbi 40%.<\/strong><\/p>\n

C\u00f3 nhi\u1ec1u nguy\u00ean nh\u00e2n khi\u1ebfn c\u00e1c b\u1ec7nh v\u1ec1 t\u00e2m th\u1ea7n gia t\u0103ng, trong \u0111\u00f3 nguy\u00ean nh\u00e2n ch\u00ednh l\u00e0 do s\u1ee9c \u00e9p trong c\u00f4ng vi\u1ec7c, h\u1ecdc t\u1eadp, s\u1ef1 nghi\u1ec7p… Stress k\u00e9o d\u00e0i g\u00e2y ra nh\u1eefng h\u1ec7 l\u1ee5y r\u1ea5t l\u1edbn cho ng\u01b0\u1eddi b\u1ec7nh. C\u00f3 h\u01a1n 90% <\/strong>s\u1ed1 ng\u01b0\u1eddi t\u1ef1 t\u1eed l\u00e0 do b\u1ecb r\u1ed1i lo\u1ea1n lo \u00e2u. C\u00f9ng v\u1edbi \u0111\u00f3, chi ph\u00ed y t\u1ebf \u0111\u1ec3 \u0111i\u1ec1u tr\u1ecb r\u1ed1i lo\u1ea1n c\u0169ng cao g\u1ea5p 3 l\u1ea7n <\/strong>c\u00e1c b\u1ec7nh n\u1ed9i khoa th\u00f4ng th\u01b0\u1eddng.<\/p>\n

\"\"<\/p>\n

H\u00ecnh 2.<\/strong> Th\u00f4ng tin v\u1ec1 stress t\u1ea1i Vi\u1ec7t Nam<\/p>\n

Tuy nhi\u00ean, v\u1ea5n \u0111\u1ec1 n\u00e0y ch\u1ec9 \u0111\u01b0\u1ee3c gi\u1ea3i quy\u1ebft \u201ct\u1ea1m th\u1eddi\u201d b\u1eb1ng c\u00e1c lo\u1ea1i thu\u1ed1c ng\u1ee7.\u00a0Nh\u01b0\u1ee3c \u0111i\u1ec3m c\u1ee7a ch\u00fang l\u00e0 g\u00e2y ra h\u00e0ng lo\u1ea1t t\u00e1c d\u1ee5ng ph\u1ee5 (\u0111au \u0111\u1ea7u, n\u00f4n \u00f3i, \u0111au bao t\u1eed, li\u1ec7t c\u01a1,\u2026); khi\u1ebfn ng\u01b0\u1eddi d\u00f9ng ph\u1ee5 thu\u1ed9c v\u00e0o thu\u1ed1c (kh\u00f4ng c\u00f3 thu\u1ed1c kh\u00f4ng ng\u1ee7 \u0111\u01b0\u1ee3c v\u00e0 ph\u1ea3i t\u0103ng li\u1ec1u li\u00ean t\u1ee5c) [2] v\u00e0 chi ph\u00ed r\u1ea5t cao. Kh\u00f4ng nh\u1eefng th\u1ebf, d\u00e2y chuy\u1ec1n s\u1ea3n xu\u1ea5t c\u00e1c lo\u1ea1i thu\u1ed1c n\u00e0y g\u00e2y \u00f4 nhi\u1ec5m m\u00f4i tr\u01b0\u1eddng \u1edf m\u1ee9c r\u1ea5t kh\u00f3 ph\u1ee5c h\u1ed3i, \u0111\u1ec3 l\u1ea1i m\u1ed9t v\u1ea5n n\u1ea1n l\u1edbn ch\u01b0a c\u00f3 l\u1eddi gi\u1ea3i. C\u00e2y l\u1ee5c l\u1ea1c l\u00e1 \u1ed5i d\u00e0i (Crotalaria assamica Benth.) l\u00e0 lo\u00e0i th\u1ef1c v\u1eadt ph\u1ed5 bi\u1ebfn, d\u1ec5 tr\u1ed3ng, v\u1edbi nhi\u1ec1u lo\u1ea1i ho\u1ea1t ch\u1ea5t qu\u00fd [3], tuy nhi\u00ean ch\u01b0a c\u00f3 r\u1ea5t h\u1ea1n ch\u1ebf nghi\u00ean c\u1ee9u trong v\u00e0 ngo\u00e0i n\u01b0\u1edbc nghi\u00ean c\u1ee9u v\u1ec1 lo\u1ea1i d\u01b0\u1ee3c li\u1ec7u n\u00e0y. C\u00e2y L\u1ee5c l\u1ea1c l\u00e1 \u1ed5i d\u00e0i th\u01b0\u1eddng ph\u00e2n b\u1ed1 \u1edf c\u00e1c v\u00f9ng c\u00f3 kh\u00ed h\u1eadu \u00f4n \u0111\u1edbi v\u00e0 c\u1eadn \u00f4n \u0111\u1edbi \u1edf Vi\u1ec7t Nam nh\u01b0 T\u00e2y Nguy\u00ean, \u0110\u00e0 L\u1ea1t, L\u1ea1ng S\u01a1n,… Trong qu\u00e1 tr\u00ecnh nghi\u00ean c\u1ee9u,\u00a0 nh\u00f3m \u0111\u00e3 ph\u00e1t hi\u1ec7n ra h\u00e0ng lo\u1ea1t t\u00ednh ch\u1ea5t m\u1edbi c\u1ee7a c\u00e2y nh\u01b0ng t\u00e1c d\u1ee5ng an th\u1ea7n gi\u1ea3i lo \u00e2u, ho\u1ea1t t\u00ednh kh\u00e1ng \u00f4xi h\u00f3a v\u00e0 ho\u1ea1t t\u00ednh kh\u00e1ng khu\u1ea9n l\u00e0 n\u1ed5i b\u1eadt nh\u1ea5t [4]. C\u00f9ng v\u1edbi \u0111\u00f3, nh\u00f3m \u0111\u00e3 t\u1ed1i \u01b0u h\u00f3a th\u00e0nh c\u00f4ng quy tr\u00ecnh chi\u1ebft xu\u1ea5t lo\u1ea1i d\u01b0\u1ee3c li\u1ec7u n\u00e0y, th\u1eed nghi\u1ec7m \u0111\u1ed9c t\u00ednh c\u1ea5p (\u0111\u1ed9 an to\u00e0n), \u0111\u00f4c t\u00ednh b\u00e1n tr\u01b0\u1eddng di\u1ec5n (t\u00e1c d\u1ee5ng ph\u1ee5) v\u00e0 ho\u1ea1t t\u00ednh an th\u1ea7n tr\u00ean m\u00f4 h\u00ecnh in vitro (d\u00f2ng t\u1ebf b\u00e0o) v\u00e0 in vivo (chu\u1ed9t) v\u00e0 k\u1ebft qu\u1ea3 cho th\u1ea5y s\u1ea3n ph\u1ea9m v\u01b0\u1ee3t tr\u1ed9i ho\u00e0n to\u00e0n c\u00e1c s\u1ea3n ph\u1ea9m tr\u00ean th\u1ecb tr\u01b0\u1eddng. Kh\u00f4ng nh\u1eefng th\u1ebf, quy tr\u00ecnh s\u1ea3n xu\u1ea5t m\u1edbi c\u1ee7a nh\u00f3m r\u1ea5t th\u00e2n thi\u1ec7n v\u1edbi m\u00f4i tr\u01b0\u1eddng, g\u00f3p ph\u1ea7n l\u00e0m gi\u1ea3m gi\u00e1 c\u1ea3, ph\u00f9 h\u1ee3p v\u1edbi ng\u01b0\u1eddi ti\u00eau d\u00f9ng. Cu\u1ed1i c\u00f9ng, t\u1eeb lo\u1ea1i d\u01b0\u1ee3c li\u1ec7u n\u00e0y c\u00f3 th\u1ec3 s\u1ea3n xu\u1ea5t \u0111a d\u1ea1ng c\u00e1c lo\u1ea1i s\u1ea3n ph\u1ea9m kh\u00e1c nhau (tr\u00e0 t\u00fai l\u1ecdc, tr\u00e0 latte hay tr\u00e0 l\u1ea1nh) v\u00e0 \u0111\u01b0\u1ee3c 85% ng\u01b0\u1eddi ti\u00eau d\u00f9ng y\u00eau th\u00edch khi kh\u1ea3o s\u00e1t s\u1ee3 b\u1ed9 (170\/200).<\/p>\n

\"\"<\/p>\n

H\u00ecnh 3. <\/strong>C\u00e2y l\u1ee5c l\u1ea1c l\u00e1 \u1ed5i d\u00e0i.<\/p>\n

\u0110\u00c3 C\u00d3 NH\u1eeeNG GI\u1ea2I PH\u00c1P N\u00c0O HI\u1ec6N NAY \u0110\u1ec2 X\u1eec L\u00dd V\u1ea4N \u0110\u1ec0 TR\u00caN<\/strong><\/p>\n

\u0110\u1ed0I TH\u1ee6 C\u1ea0NH TRANH<\/strong><\/em><\/p>\n

+ C\u00e1c thu\u1ed1c an th\u1ea7n k\u00ea theo ch\u1ec9 \u0111\u1ecbnh (ETC): Diazepam, Lorazepam, Alprazolam, …<\/p>\n